etymologeek.com dictionary
English word lonesome comes from English -some, English lone.

Lonesome etymology history

Lonesome detailed word origin explanation

Dictionary entryLanguageDefinition
-some English (eng) Characterized by some specific condition or quality. Used to form a word indicating a group with a certain small number of members A body A chromosome.
lone English (eng) (archaic) Single; unmarried, or in widowhood.. (archaic) Unfrequented by human beings; solitary.. Isolated or lonely; lacking companionship.. Situated by itself or by oneself, with no neighbours.. Sole; being the only one of a type.. Solitary; having no companion.
lonesome English (eng) Unhappy due to being alone; lonely. (informal) Oneself alone.

Words with the same origin as lonesome

Descendants of -some
awesome fearsome threesome tiresome troublesome