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English word regardless comes from English -less (Lacking (something); without (something).), English regard.

Regardless etymology ?

Regardless detailed word origin explanation

Dictionary entryLanguageDefinition
-less English (eng) Lacking (something); without (something).
regard English (eng) (transitive) To consider, look upon (something) in a given way etc. [from 16th c.]. (transitive) To face toward.. (transitive) To have to do with, to concern. [from 17th c.]. (transitive, archaic) To take notice of, pay attention to. [from 16th c.]. (transitive, obsolete) To set store by (something), to hold (someone) in esteem; to consider to have value, to respect. [from 16th c.]. To look [...]
regardless English (eng) Having no regard; heedless; careless. Paying no attention to; regardless of. Without attention to warnings or indications of bad consequences.

Words with the same origin as regardless

Descendants of -less
breathless clueless countless defenseless fearless flawless hopeless meaningless merciless needless penniless pointless priceless relentless ruthless selfless senseless sleepless thoughtless timeless toothless topless useless wireless